Common treatments for hot flashes in men include venlafaxine, an antidepressant, and medroxyprogesterone acetate and cyproterone acetate, two hormone therapies, states Healthline. About 83 percent of men taking estradiol and 80 to 90 percent taking megestrol and medroxyprogesterone experience relief. The antiseizure drug gabapentin also reduces male hot flashes.
Men being treated with androgen deprivation therapy for prostate cancer sometimes experience hot flashes. The therapy treats the cancer by reducing testosterone levels, but decreased testosterone often produces hot flashes, notes Healthline. Up to 80 percent of men who undergo androgen deprivation therapy display the symptoms, which are the same for men and women. Hot flashes are sudden, intense feelings of heat and flushing in the head and torso, with profuse sweating and reddening of the skin. They last about four minutes.