While they vary depending on the individual and metal levels in the blood, common symptoms of metallosis include darkened tissue around an implant, pain, instability and fluid-filled pockets surrounding the affected tissue, according to Drugwatch.com. Patients may also experience symptoms related to the nervous system, skin, heart and other organs.
Metallosis, or metal poisoning, may occur after a patient receives a metal-on-metal hip or knee implant and often causes the death of bone and tissue, as stated by Drugwatch.com. This necrosis may cause the tissue around the implant to turn gray or black, and the potential instability can lead to fractures and spontaneous dislocation. The non-cancerous pockets that sometimes form on the tissue may fill with cloudy yellow, rust-colored or gray fluid.
Other symptoms of metallosis include nerve issues, cognitive impairment, heart problems, thyroid problems, rashes on the skin, loosening of the implant and infection, as explained by Drugwatch.com. Metallosis may also cause auditory and visual impairment that may lead to deafness and blindness. Studies have found a number of symptoms specific to serum cobalt poisoning, including memory problems, pseudotumors, vertigo, trouble concentrating, depression, goiter and seizures. Patients who believe they may be suffering from metallosis should contact a doctor immediately for diagnosis and testing.