Intravenous iron supplementation is often provided to anemic patients who cannot take oral iron vitamins, according to the Cleveland Clinic. While side effects are minimal, common side effects are lightheadedness when getting up from a sitting or lying position and bloating of the face, arms, hands and lower legs.
Other side effects reported by patients include gastrointestinal pains, breathing problems, skin rashes, low blood pressure and chest pain, notes the Cleveland Clinic. Anaphylaxis, a severe allergic reaction that is life threatening, can happen, but is rare.
Intravenous iron supplementation may be ideal for individuals who have developed severe anemia due to iron-poor diets, kidney failure or are on blood thinners such as heparin, explains the Cleveland Clinic. Other iron supplementation methods should be tried first, though.