The main side effects of D-mannose include loose stools and bloating, according to WebMD. It is possible that D-mannose can make it more difficult to control blood sugar, and it may also cause kidney damage. D-mannose is similar to glucose.
D-mannose is used to treat carbohydrate-deficient glycoprotein syndrome type 1b, a rare condition, claims WebMD. This condition is hereditary, and it causes sufferers to lose protein through the intestinal tract. When taking D-mannose, the protein loss slows, and the patient's liver may work better. In addition, it can also help to reduce any associated bleeding issues and low blood sugar in people who have this condition. D-mannose is also taken to treat urinary tract infections, and in studies on mice, the results show that it may also help to prevent the development of urinary tract infections.
Studies also show that D-mannose can take a role in the body as a prebiotic, explains WebMD. These prebiotics can help the body by helping the good bacteria in the digestive system develop. In these studies, it shows that those who suffer from conditions such as dysbiosis, which is an imbalance of bad and good bacteria, may find relief by taking D-mannose. There are some ways to get D-mannose naturally, such as eating foods including apples, peaches, oranges and some berries including cranberries and blueberries.