What Are the Most Common Painkillers?

What Are the Most Common Painkillers?

Nonsteroidal anti-inflammatory drugs (NSAIDS), aspirin, acetaminophen and narcotics are the most common pain-relief medications, according to eMedicineHealth. NSAIDS, such as Aleve and Motrin, are widely available over the counter, as is acetaminophen, which is branded as Tylenol, and aspirin. Narcotics are only available with a doctor's prescription, and include drugs like hydrocodone, oxycodone, Endocet, Percocet and Stagesic, among others.

NSAIDS are also available in prescription formulas, including Daypro, Lodin, and Nalfon, reports eMedicineHealth. NSAIDs work by reducing inflammation and acting on the centers of the brain that control pain sensations. Acetaminophen combined with narcotic drugs is also available only with a doctor's order. This pain medication is formulated with codeine, oxycodone or hydrocodone and Tylenol.