Common hormone replacement therapy, or HRT, drugs include Ortho-Prefest, Activella, Premphase, FemHrt and Prempro, according to MedlinePlus. By replacing estrogen and progestin hormones, HRT drugs treat menopause symptoms such as vaginal itching and thinning of bones, while also reducing the uterine cancer risk.
Women taking HRT drugs may experience side effects such as headaches, diarrhea, stomach cramps and spotting between periods, as stated by MedlinePlus. More serious HRT side effects, such as double vision and yellowing of the skin, require immediate medical attention. Additionally, HRT drugs may increase the risk of stroke, heart attack, breast cancer, endometrial cancer and gallbladder disease.