Some common side effects of coenzyme Q-10 are nausea, vomiting, diarrhea, skin rashes and lowered blood pressure, according to WebMD. These side effects are usually mild. Patients with very low blood pressure need to monitor their blood pressure carefully while taking coenzyme Q-10.
Coenzyme Q-10 is a vitamin-like substance, naturally found in the body, that is used to treat a variety of conditions, states WebMD. It has been found likely effective in treating mitochondrial disorders and coenzyme Q-10 deficiency, and probably effective in treating many other conditions, including congestive heart failure, diabetic neuropathy, high blood pressure, migraine headaches and Parkinson’s disease. For these conditions, patients take coenzyme Q-10 orally. Research into using topical coenzyme Q-10 treatments for gum disease have been inconclusive as to its effectiveness.
Research shows coenzyme Q-10 likely safe for adults in both its oral and topical formulations, maintains WebMD. Taking smaller doses spread throughout the day lowers the risk and severity of side effects. Children and pregnant women require medical supervision when taking coenzyme Q-10, and breastfeeding women should avoid the medication. Coenzyme Q-10 may interfere with the effectiveness of chemotherapy and increase the effectiveness of certain blood pressure medications. Because of the effect of coenzyme Q-10 on blood pressure, doctors often recommend avoiding it for two weeks before a surgical procedure.