The most common causes of hot hands are peripheral nerve damage and carpal tunnel syndrome, according to the National Institute of Neurological Disorders and Stroke. Physical skin burns, Lyme disease and vitamin deficiencies can also create a burning sensation in the hands.
Peripheral neuropathy affects the extremities and causes a burning sensation, says WebMD. Carpal tunnel syndrome also interferes with nerves in a way that creates a burning feeling in the hands. Often these causes of neuologically-based burning sensations come with numbing or tingling in addition to the burning feeling.
Burning caused by peripheral neuropathy may be acute or chronic, explains the National Institute of Neurological Disorders and Stroke. Damage to the peripheral nerves often results in the nerves sending confusing signals back to the brain that the brain interprets as heat. Trauma, autoimmune deficiencies or even cancer can bring about the underlying nerve damage. Similarly, carpal tunnel syndrome inflames the nerves in a way that often produces a burning sensation.
Another common cause of hot hands is skin burn. In addition to heat, a skin burn causes visible damage to the hands, such as blisters, swelling and skin changes, says WebMD. Reactions to stress also causes hot hands. As a person reacts to stress or anxiety, nervousness and its associated body chemistry changes cause hands to feel hot. Lyme disease is a bacterial infection that causes inflammation. In turn, the inflammation causes hot hands. Allergies also often contribute to an inflammation across the entire body, including in the hands, creating a burning sensation in the body's extremities.