The most common adverse side effect of statins is myalgia, or pain in the muscles, claims Mayo Clinic. The patient's muscles may feel sore or weak, and the pain can range from mild to severe. Rarely, statin use leads to life-threatening muscle damage that can affect vital organs.
Other adverse side-effects of statins are liver damage as the liver increases its production of digestive enzymes, claims Mayo Clinic. This is why it is important for a patient to have a liver enzyme test before she begins taking statins.
Statins may not only cause muscle pain but can cause muscle inflammation, or myositis, according to WebMD. If the statins are taken with other medications, they can increase the patient's risk of muscle injury. Statins can also raise the levels of the muscle enzyme creatine kinase, which can also lead to pain and weakness. This condition can take a while to reverse.
Patients on statins can also suffer headache, insomnia, flushing skin and rash, dizziness and drowsiness. Other possible symptoms include confusion, memory loss and gastrointestinal issues. Statin use may also put some people at higher risk for Type 2 diabetes, claims WebMD. People with liver disease and pregnant women should not use statins.