It is recommended that consumers choose a SAM-e brand that has a good reputation, according to About.com. Since SAM-e is not regulated in the United States, caution should be used when taking it.Continue Reading
Those who take SAM-e should also take vitamin B supplements, states About.com. SAM-e works together with these vitamins and becomes more effective. SAM-e should only be used by individuals who are under the care of a doctor, and the dose should not exceed more than 1,200 milligrams per day.
Most people who take SAM-e take it for osteoarthritis relief, and in many cases, it may work better than traditional osteoarthritis medications, explains About.com. Research shows that SAM-e is just as effective as non-steroidal anti-inflammatory drugs when reducing pain and improving motion. It has also been found to have fewer side effects for patients. In addition, SAM-e has been shown to be just as effective as Celebrex after taking the supplement for more than two months. SAM-e, however, is slower to become effective in the first month of use for most patients.
There are side effects associated with SAM-e, warns About.com. These side effects include nausea, diarrhea, flatulence, vomiting and headache. There is also the possibility of negative interactions with antidepressants and may worsen symptoms of Parkinson's disease.Learn more about Vitamins & Supplements