Trembling during sleep, or myoclonus, can be the result of neurological disorders and atrophies, endocrine dysfunction, liver problems, diabetes, neurological injury, or diseases such as Parkinson's or Alzheimer's, notes Mayo Clinic. Alcohol withdrawal or the use of certain drugs, such as amphetamines, can also cause sleep tremors, explains Healthline.
Chemical or drug poisoning or prolonged oxygen deprivation can lead to neurological problems that result in sleep tremors. Autoimmune inflammatory conditions can also result in sleep tremors, according to Mayo Clinic. Hypothermia can trigger trembling while sleeping as well. In some cases, exhaustion could result in sleep tremors, reports Healthline. These tremors subside after a person has rested.