Benign tingling in the feet and toes is often caused by pressure on the nerves occurring when a person crosses her legs for too long, explains WebMD. Chronic or severe tingling in the extremities is caused by more serious conditions, such as diabetic neuropathy, vitamin deficiencies or infections.
Patients with persistent tingling in the hands, feet or both should seek prompt medical evaluation, advises WebMD. Detecting and treating the underlying cause of the tingling early reduces the risk of lifelong consequences. For many patients, tingling in the extremities is one of the first signs of diabetes. About two-thirds of all diabetics have some degree of peripheral neuropathy.
A deficiency in vitamin E, B-1, B-6 or B-12 can also lead to tingling in the extremities, explains WebMD. These vitamins are all necessary for proper nerve function. Too much vitamin B-6 can also cause tingling. Alcoholics are more likely to experience tingling in the hands and feet, since they are prone to vitamin deficiencies because of poor dietary habits.
Infections, including Lyme disease, cytomegalovirus and HIV/AIDS, are also known to cause tingling in the extremities, according to WebMD. Inherited disorders, such as Charcot-Marie Tooth disease, and autoimmune diseases, such as lupus and rheumatoid arthritis, may cause tingling as well.