There are many potential causes for tingling in the hands, such as diabetes, systemic diseases and vitamin deficiencies, notes WebMD. Exposure to toxins from the environment or some medical treatments, such as chemotherapy, can cause neuropathy, or tingling in the hands. Injury, inherited disorders and autoimmune diseases are all possibilities.
Diabetes is the No.1 cause of tingling in the hands and feet, accounting for 30 percent of cases, as two-thirds of people with diabetes have some degree of damage to nerves, states WebMD. This is often the first sign that a person has diabetes. Another 30 percent of cases are referred to as idiopathic, meaning the cause for tingling in the extremities is unknown. The other 40 percent of cases have a wide array of causes.
Nerve entrapment syndromes, such as carpal tunnel or nerve palsy, are possible causes of hand tingling, according to WebMD. Systemic diseases, such as kidney or liver disease, hypothyroidism or cancer, can cause pressure on the nerves. A vitamin B-12 deficiency is often a cause for peripheral neuropathy, although too much vitamin B-6 can have the same effect. Alcoholism often causes a thiamine deficiency, which is another cause for neuropathy. Infections, such as AIDS, Lyme disease or herpes simplex, may also be the cause of tingling in the hands. Rheumatoid arthritis, Charcot-Marie-Tooth disease and lupus may induce neuropathy as well.