Thigh muscle pain can be a symptom of common minor leg injuries caused by overuse, exercise, and everyday wear and tear, according to WebMD. Pain can also result from medical conditions including dehydration, peripheral arterial disease and thrombophlebitis.
Dehydration can occur if a person loses too many fluids or doesn't consume enough of them, notes MedlinePlus. Conditions that can lead to dehydration include diabetes and stomach viruses. Dehydration can produce mild symptoms such as muscle cramps and headache. In cases of severe dehydration, people can experience dry skin, a rapid heartbeat and shock.
Peripheral arterial disease occurs when plaque builds up in the body's arteries, causing a lack of blood flow to various parts of the body, explains the National Heart, Lung and Blood Institute. The condition commonly affects arteries in the legs and causes symptoms of pain and numbness in affected regions. Smoking, age and certain conditions can increase the risk of having the disease.
Thrombophlebitis is a condition in which a blood clot blocks one or more veins, according to Mayo Clinic. It can be caused by prolonged inactivity, surgery or trauma, and the type of symptoms depend on the proximity of the affected vein to the surface of the skin. If the vein is close to the surface, a person may see a hard and red cord under the surface of the skin, while veins deeper in the leg can cause symptoms such as warmth and swelling in affected areas.