Sharp, stabbing thigh pain can be caused by several factors that include nerve damage, muscle strains, infected tissues and blood clots, according to Healthline. It is important for individuals with unexplained thigh pain to consult with a physician if the pain persists or if pain occurs when walking.
Sharp thigh pain can also be caused by sciatica, a condition in which the nerve that travels from the back down both legs becomes inflamed, according to WebMD. Additional symptoms of sciatica include a burning sensation that travels down the leg, hindered leg mobility, pain in the rear end and pain that is exacerbated when sitting. Sciatica can occur during pregnancy and is also caused by degenerative disc disease, a condition in which the spinal discs wear down.
Stabbing thigh pain can also indicate a muscle cramp, according to Mayo Clinic. Muscle cramps cause intense, shooting pain that is often accompanied by a lump directly underneath the skin. It is important for individuals with muscle cramps to seek medical attention if their symptoms are accompanied by leg swelling, inflammation or weakness of the leg muscles. Mayo Clinic adds that muscle cramps can occur for several reasons, including dehydration, compressed nerves and holding one body position for an extended period of time. Low levels of potassium in the body can also contribute to muscle cramps.