What Causes Pustular Psoriasis?


Quick Answer

Most researchers believe that a combination of genetic and environmental factors cause pustular psoriasis, and possible triggers include strong topical solutions, certain medications and the abrupt stopping of high-dose systemic steroid use, confirms eMedicineHealth. Doctors are unable to identify the exact trigger in most patients.

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Full Answer

The medications that may exacerbate pustular psoriasis include lithium, the antimalarial medication hydroxychloroquine, nonsteroidal anti-inflammatory drugs, oral iodides, and recombinant interferon-beta and interferon alfa injections, according to eMedicineHealth. Topical products that may trigger the condition include anthralin and tar. Other potential triggers include pregnancy, excess exposure to ultraviolet rays, emotional stress and infection, adds the National Psoriasis Foundation. Possible types of pustular psoriasis include palmoplantar pustulosis, which often affects the inside of the heels and the base of the thumbs, the rare form known as acropustulosis, and the potentially life-threatening Von Zombusch.

Patients can prevent pustular psoriasis flare-ups by avoiding environmental triggers known to bring about psoriasis in general, including smoking and alcohol, recommends eMedicineHealth. Although there are no known supplements or dietary changes that can prevent psoriasis, patients should consume a well-balanced diet. Exposure to the sun can often trigger psoriasis, but it can also relieve it in some people. Sufferers should contact a doctor to discuss potential triggers and treatment options.

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