Some causes of pain in the back of the thigh include sciatica, cellulitis, a pulled hamstring muscle, a bone injury and hip pain that radiates to the thigh, explains Healthgrades. More serious conditions include deep vein thrombosis, peripheral neuropathy and peripheral artery disease.
Thigh pain that occurs with other symptoms, such as fainting, chest pain, shortness of breath and a discolored and unusually cold leg, may indicate deep vein thrombosis, reports Healthgrades. This happens when a blood clot forms in a vein and travels towards the lungs. Ice and anti-inflammatory drugs may help mild conditions, but deep vein thrombosis and other serious conditions need medical attention.