Besides dehydration, other causes of orange urine include urinary system conditions, such as pyelonephritis and cystitis, which affect the kidney and the urinary bladder respectively, and kidney diseases, including kidney stones and kidney failure, according to Healthgrades. Eating beta-carotene supplements and foods that contain orange or red dye; using medications, including warfarin and phenazopyridine; having high bilirubin levels in the serum; and general diseases may also result in orange urine.
Diseases that may turn the urine color to orange without necessarily attacking the urinary system include prostatitis, prostate and bladder cancers, renal cell cancer and acute hepatitis, as Healthgrades notes. Liver diseases, including liver failure and liver cirrhosis, are other diseases that may cause orange urine.
Orange urine may indicate a serious underlying cause, says Healthgrades. As a result, it is advisable to visit a doctor immediately when the condition persists or when it occurs alongside symptoms including high body temperature, retention of the urine by the urinary system, severe pain in the abdomen and lower back, and vomiting that does not improve. Early treatment helps to prevent possible complications, such as cancer spread, sepsis, and kidney and liver damage. To determine the cause of orange urine, a doctor may seek to know, among other information, when the condition started, the patient's urination frequency, the smell of the urine and other urine characteristics. The patient should also notify the doctor about other symptoms that accompany orange urine and any medications he currently takes.