Nose dryness can be caused by a dry environment and certain medications, or in rare situations, by Sjögren's syndrome, according to Healthgrades. Dry environmental conditions due to climate or an air conditioner dry up the nose, which can lead to respiratory problems.
Other common environmental conditions that lead to nose dryness include indoor heating and a sauna without steam, notes Healthgrades. Common medications, such as antibiotics, antihistamines and decongestants, can also result in a dry nose. People who abuse congestion relieving drugs, such as nasal sprays, can experience nose dryness as well.
Sjögren's syndrome is an autoimmune condition that occurs when the immune system destroys the body's moisture-producing glands, according to Cleveland Clinic. Areas of the body that may be affected include saliva-producing and tear-producing glands, lungs and bowels. A person with Sjögren's syndrome may experience enlarged parotid glands and often has extremely dry eyes and mouth, a decreased sense of taste, fatigue, and an increase in dental cavities. Less common symptoms include skin rashes, memory loss, inflammation of certain organs, lymphatic cancer and thyroid gland abnormalities.
Sjögren's syndrome can be of two forms, primary or secondary, explains Cleveland Clinic. In primary Sjögren's syndrome, the disease is not associated with other illnesses, whereas in secondary Sjögren's syndrome, the disease arises due to another autoimmune condition, such as psoriatic arthritis. There is no known cause for the disease, but factors such as the environment, abnormal immune response, sex hormones and inheritance can contribute to it.