What Are Some Causes of Lytic Lesions in the Hip?


Quick Answer

Osteolytic lesions, or lytic lesions, are a common symptom of myeloma, according to About.com. These commonly occur in the pelvis, spine, skull and ribs. Osteolytic lesions are possible but rare in patients with prostate cancer, states Medscape. Other possible causes are metastatic neuroblastoma and Ewing's sarcoma in children and teenagers and metastasis in adults.

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Multiple myeloma causes osteolytic lesions by preventing the growth of normal, healthy bone cells and increasing the body’s production of osteoclasts, which break down bone cells, states the Multiple Myeloma Research Foundation. Osteolytic lesions create soft spots in the bone that can be painful to the patient, increase the risk of broken bones or cause spinal compression. Around 85 percent of patients with multiple myeloma display symptoms of osteolytic lesions, which look like holes in the bone on an X-ray scan.

Multiple myeloma is a type of cancer that effects plasma cells that reside in the marrow of bones, states WebMD. Plasma cells grow at an accelerated rate and push out red and white blood cells. In addition to bone lesions, this can weaken the immune system, lead to kidney problems or cause anemia. Other symptoms of multiple myeloma include weight loss, confusion, fatigue, difficulty breathing and bruising.

There is no cure for multiple myeloma, but treatments reduce symptoms and extend the life of patients, as of 2015. Elderly male African-Americans and overweight individuals have increased risk of developing the condition, explains WebMD.

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