A low level of enzymes in the liver generally indicates a healthy liver, according to U.S. Department of Veterans Affairs. However, it is still possible for patients with normal liver enzymes to have liver damage.
When liver enzyme levels are high, the liver may be unhealthy, notes the VA. Heightened enzyme levels can also indicate issues with other organs or the bile ducts. When interpreting liver enzyme tests, doctors look for two enzymes made by the liver: AST and ALT. The liver passes these enzymes into the bloodstream as a result of liver damage. Higher than normal values indicate liver damage, which often results from use of over-the-counter or street drugs, or infection with the hepatitis C virus.