Some causes of low immunoglobulin include certain medications, burns and medical conditions such as kidney failure, nephrotic syndrome and diabetes, according to Lab Tests Online. The most common causes of low immmunoglobulin are medical conditions that either increase protein loss in the body or affect the production of immunoglobulins.
Kidney failure occurs when the kidneys stop filtering waste from the blood in adequate amounts, notes Healthline. Factors that can lead to kidney failure include toxic exposure, kidney damage and diseases such as scleroderma. When the kidneys stop filtering waste, toxins accumulate in the body, leading to kidney failure and death. Symptoms of kidney failure include edema, nausea, pain in the chest and seizures.
Nephrotic syndrome describes a group of symptoms, including low levels of protein, high levels of cholesterol and high triglyceride levels in the blood, according to MedlinePlus. The condition is caused by diseases that damage the kidneys, with minimal change disease and membranous glomerulonephritis being the most common. Edema is the most common symptom of nephrotic syndrome, but loss of appetite and weight gain can also occur.
Diabetes is a chronic disease that causes blood glucose levels in the blood to become abnormally high, explains MedicineNet. The condition occurs due to a lack of insulin, defective insulin or problems with insulin uptake by cells. Patients with diabetes experience symptoms such as thirst, fatigue and hunger, and can get acute or chronic complications, including hyperglycemia and disease of the blood vessels.