What Are Some Causes of Hodgkin's Lymphoma?


Quick Answer

As of 2015, the cause of Hodgkin's lymphoma is unclear, notes Mayo Clinic. Doctors believe that most Hodgkin's lymphoma cases result from the development of a mutation in the DNA of a B cell, causing cells to divide rapidly and continue living, crowding out healthy cells.

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Experts believe that the virus that causes infectious mononucleosis, called the Epstein-Barr virus, can also cause Hodgkin's lymphoma, states WebMD. Children born of a parent with Hodgkin's lymphoma

are more likely to develop the disease. Hodgkin's lymphoma also is more prevalent in men than women, people between 15 and 30 years old, and people with weak immune systems due to conditions such as HIV/AIDS, says Mayo Clinic.

Hodgkin's lymphoma is a cancer of the lymphatic system, which is a network of nodes that removes waste products from the body and produces white blood cells to protect the body against infections, according to WebMD. Symptoms include persistent fatigue, night sweats, loss of appetite and fever, explains Mayo Clinic. Patients with symptoms of Hodgkin's lymphoma should see their health care providers. Tests include physical exams for swollen liver, spleen, neck and groin; blood tests to detect the presence of cancer; surgery to remove swollen lymph nodes; and imaging tests, such as computerized tomography and X-ray. The primary aim of treatments for Hodgkin's lymphoma is to destroy as many abnormal cells as possible and include radiation therapy, stem cell transplant and chemotherapy.

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