Q:

What causes high white blood cell count and low anticoagulant in the blood?

A:

Quick Answer

Particular causes of high white blood cell count include allergic reactions, acute lymphocytic leukemia, chronic lymphocytic leukemia and rheumatoid arthritis. They also include drugs, stress, smoking, tuberculosis, whooping cough, myelofibrosis and certain bacterial and viral infections, according to Mayo Clinic.

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Full Answer

A high white blood cell count may occur due to an increased production of white blood cells to fight an infection; an immune disorder that increases white blood cell production; a bone marrow disease that causes an abnormally high production of white blood cells; or a reaction to a drug that increases white blood cell production, states Mayo Clinic.

In the case of low anticoagulant in the blood, this is an inherited condition, according to Lipe et al. for the American Heart Association journal. Certain people born with deficiencies of one of the natural anticoagulants in the blood inherit an abnormal gene. In some cases, low anticoagulant in the blood may be caused by certain conditions such as liver disease, pregnancy, vitamin K deficiency, severe infections and medications such as estrogen and heparin.

Deficiencies of anticoagulants in the blood are associated with increased risk for blood clots in veins but play no role in the development of blood clots in arteries, explains Lipe et al. However, this risk can be reduced with a lifestyle change and medication.

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