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What causes Grover's disease?

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Quick Answer

As of 2015, the cause of Grover's disease is unknown, according to WebMD. However, the disease is believed to be associated with trauma to skin damaged by the sun. Grover's disease may be linked to exposure to extreme temperatures, according to the American Ostepathic College of Dermatology.

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What causes Grover's disease?
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Full Answer

Also known as transient acantholytic dermatosis or TAD, Grover's disease is rare, but most common in men over the age of 40, according to WebMD. The main symptom of the disease is itchy, red spots on the trunk, states the AOCD.

The red spots appear as groups of small blisters with a swollen border around them, according to WebMD. Grover's disease is diagnosed with a microscopic evaluation of a skin shave biopsy, states the AOCD. Under a microscope, Grover's disease is evident because of the characteristic lysis of skin cells due to the loss of the substance holding the cells together.

The course of Grover's disease is usually between less than a year, although the disease can last longer, warns the AOCD. Topical, prescription strength cortisone creams can treat a minor case of Grover's disease. Accutane, tetracycline, PUVA phototherapy treatment, cortisone injections or antifungal pills are used to treat more severe case of the disease.

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