The main cause of gout in the foot is the buildup of too much uric acid in the blood. The cause of hyperuricemia,Â orÂ uric acid buildup, is not known, but it is commonly attributed to genetic factors, according to WebMD. The build up of uric acid leads to the formation of crystals in the joints, which leads to pain, swelling, heat and other symptoms.
Uric acid buildup leads to kidney stones in the kidney, uric acid deposits under the skin and deposits of crystals in the joints, especially in the big toe. Most people usually experience gout in the big toe, which causes disturbances during sleep. This is because the toe swells and becomes red and sore. Other areas that are affected by gout include fingers, ankles, heels, knees, wrists and elbows. Fortunately, a person with gout can get well after 3 to 10 days without using any medication.
Drugs that may increase the risk of gout include niacin, aspirin, diuretics and medications for high blood pressure. Men are at a higher risk of getting gout because they experience a higher uric acid buildup during puberty than women. Medical conditions, such as kidney disease, diabetes, high blood pressure, osteoarthritis and high cholesterol levels, can increase the chances of getting gout.