Common causes of extreme tiredness include using or abusing alcohol, consuming caffeinated beverages, excessive physical activity and a lack of sleep, according to Mayo Clinic. Other causes of extreme fatigue include poor dietary habits and prolonged periods of inactivity.
Fatigue is usually caused by lifestyle choices, medical conditions or psychological issues, notes Mayo Clinic. Some medications, such as cold remedies, cough medicines and antihistamines, may cause extreme tiredness. Other medications that may cause fatigue include some antidepressants, heart medications, prescription pain medications and blood pressure medications. People with mental health problems, such as stress, grief, depression and anxiety, may experience exhaustion as a symptom.
Medical conditions that may cause extreme tiredness include type 1 and type 2 diabetes, sleep apnea, heart disease and restless legs syndrome, states Mayo Clinic. Anemia, acute liver failure, chronic fatigue syndrome or cancer may also cause fatigue. Other medical problems that may cause excessive tiredness include chronic kidney disease, COPD, obesity, and an underactive or overactive thyroid.
If extreme tiredness lasts for more than two weeks in spite of attempts to follow a normal sleep schedule, contact a doctor, recommends Mayo Clinic. If the fatigue also includes severe headaches, abnormal bleeding, or severe back, pelvic or abdominal pain, seek immediate medical assistance. Medical attention is also required if fatigue is accompanied by shortness of breath, chest pain, an irregular heartbeat or the feeling of potentially passing out.