Causes of acquired hemolytic anemia vary depending upon the type of the condition and include certain medications, certain medical conditions, blood clots and blood transfusion, states Everyday Health. Types of acquired hemolytic anemia include autoimmune hemolytic anemia, drug-induced hemolytic anemia, mechanical hemolytic anemia and alloimmune hemolytic anemia.
Studies show that certain disorders, including Epstein-Barr virus, lupus, lymphoma and leukemia may render a person vulnerable to autoimmune hemolytic anemia, explains Everyday Health. Hepatitis and human immunodeficiency virus may also increase the risk for the condition. Anti-inflammatory medications, acetaminophen, penicillin and medications for malaria may cause the body to attack red blood cells, causing anemia.
Certain activities may weaken and damage red blood cells, leading to mechanical hemolytic anemia, notes Everday Health. Blood clots and tumors in small blood vessels may trigger the destruction of erythrocytes. Pregnant women who suffer from preeclampsia are at a higher risk of developing this form of anemia. Alloimmune hemolytic anemia occurs when the immune system of a blood recipient destroys the foreign red blood cells.
Immunosuppressants, medications that boost the production of red blood cells and blood transfusion may provide short-term relief for patients with acquired hemolytic anemia, according to Everyday Health. Plasmapheresis, which is a method of removing destructive antibodies from the blood, may help as well. Bone-marrow stem cell transplant and surgery to remove the spleen are long-lasting treatment options.