What Are Some Cardiovascular Side Effects Caused by Celebrex?


Quick Answer

Cardiovascular side effects caused by Celebrex include myocardial infarction, stroke and serious cardiovascular thrombotic events, according to Drugs.com. Celebrex should also not be used to treat perioperative pain in the course of coronary artery bypass graft surgery.

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Full Answer

Celebrex causes side effects such as sore throat, cold symptoms, diarrhea and gas. If the patient experiences some serious side effects such as unusual bleeding or bruising, unexplained weight gain, pain in the upper right part of the stomach, yellowing of the eyes or skin, and swelling of the throat, face, tongue, feet, and lower legs or ankles, he should seek immediate medical attention, cautions MedlinePlus. Celebrex may also raise the patient’s blood pressure and, in rare conditions, cause liver damage, says WebMD.

Celebrex is a nonsteroidal anti-inflammatory drug that works by blocking the enzyme that makes prostaglandins in the body, says WebMD. It is used to relieve swelling, stiffness, pain and tenderness caused by osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis and ankylosing spondylitis, which is arthritis that mainly affects the spine, according to MedlinePlus. It is also used to treat painful menstrual periods and relieve other types of pain from surgery, injuries, and other medical procedures or conditions.

An expectant mother should not use Celebrex during the first and last trimesters of pregnancy, as it could harm the unborn child and interfere with normal delivery, warns WebMD. Celebrex also passes into breast milk.

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