Lidocaine topical ointment, available over the counter, is able to be used on the vagina to relieve itching or pain, according to MedicineNet. If used as directed, there are very few side effects to be expected, and those few are minor.
Side effects may include redness, swelling and stinging that should quickly subside. If they don't pass quickly, a doctor should be consulted, states MedicineNet.
It is rare that more serious side effects occur. These severe reactions can include worsening of redness or rash, new areas of rash and any swelling, especially in the facial and oral areas, such as the tongue or throat. If there is any trouble with breathing, emergency medical assistance should be sought immediately, warns MedicineNet.