Tylenol and Naproxen can be taken together, as there are no drug interactions between the two, according to BJC HealthCare. The dosage of the Naproxen and the Tylenol will not matter, as the two drugs do not cross react; however, proper dosage of both drugs should be taken based on the recommendations of a medical professional. Naproxen should be taken with food, although Tylenol can be taken on an empty stomach.
Both Tylenol and Naproxen are designed for pain-relief purposes, and both can be purchased without a prescription. Take note that the daily intake of Tylenol should be limited to 3,000 mg to prevent liver problems from arising.