Patients taking statins most commonly experience muscle pain as a side effect, according to Mayo Clinic. However, joint pain is not commonly recognized as a statin side effect, and pain occurring in one joint is extremely rare, according to the National Center for Biotechnology Information.
Patients taking statins, which are prescribed to lower cholesterol levels, may experience tired, sore or weak muscles. The muscle pain is sometimes merely uncomfortable, or it is severe enough to impact the patient's daily routine, such as climbing the stairs, states Mayo Clinic. Statins often trigger or aggravate joint pain in older patients, including those with osteoarthritis, notes the National Center for Biotechnology Information.