In rare cases it is possible for individuals with compromised immune systems to contract shingles from the vaccine, states Healthline. Those who have healthy immune systems do not face this risk, as the varicella zoster virus in the vaccine is weakened.
Shingles is a rash caused by the same virus as chickenpox, explains Healthline. Individuals who have contracted chickenpox as children retain the virus in their bodies, although it lies dormant. This virus can reactivate years later, and approximately half of all shingles cases affect those 60 or older. Zostavax, the shingles vaccine, reduces the likelihood of developing shingles by half. Individuals allergic to gelatin or neomycin may suffer allergic reactions to Zostavax.