The serum glutamic pyruvic transaminase, or SGPT, level can be reduced by addressing why it's elevated. High SGPT indicates that the liver has suffered damage, explains eMedicineHealth.com. An individual presenting with elevated SGPT needs a thorough work-up to discover why it's elevated before treatment can be offered.Continue Reading
SGPT is more commonly called alanine aminotransferase, or ALT. A number of different diseases, medications and conditions can cause elevated ALT, states eMedicineHealth.com. Viral hepatitis, alcohol abuse, hematochromotosis and heart failure are all common causes of elevated ALT. Taking common medications such as acetaminophen, naproxen and statins can also increase ALT levels, as can obesity, mushroom poisoning, pregnancy, gallstones and certain types of cancer.
Elevated ALT levels may cause no symptoms or may cause fatigue, nausea, vomiting and jaundice, reports eMedicineHealth.com. ALT tests are usually performed as part of routine health screening or as an evaluation for abdominal pain. Aspartate aminotransferase tests are often performed at the same time as ALT tests. The AST-to-ALT ratio can indicate if elevated ALT levels are probably due to alcohol abuse, explains WebMD.
An ALT test is performed on a basic blood sample. Because exercise can affect ALT levels, individuals may be asked to avoid strenuous exercise before testing. Normal ALT levels for men are 10 to 40 units per liter, and for women, they are 7 to 35 units per liter, reports WebMD.Learn more about Medical Ranges & Levels