There are proven cases where individuals develop work-related allergic reactions to glue, based on a 2008 published study in the United States Library of Medicine under the National Institutes of Health. The results showed that 10 patients developed contact dermatitis from sensitivity to methacrylate and acrylate, which are two active ingredients found in glues.
The study was conducted at the Finnish Institute of Occupational Health, spanning 12 years of screening tests from 1994 to 2006. All tested patients were found to react with 2-hydroxyethyl methacrylate and ethyleneglycol dimethacrylate.
Allergic reactions can also be induced in people who are constantly exposed to latex. Most adhesives, including glues and glue pens, contain latex that may trigger a latex allergy, as stated by WebMD.