OxygenHealingTherapies.com lists doctors who use Prolozone therapy. The list indicates those doctors who have learned Prolozone therapy from its founder, Dr. Frank Shallenberger. Dr. Shallenberger's course is the only accredited ozone therapy course in North America, according to Oxygen Healing Therapies.com
Prolozone therapy is derived from prolotherapy, which is a medical injection of sugar water or saline into an injured cartilage or ligament that stimulates healing after causing an initial inflammatory response, according to the Foundation for Alternative and Integrative Medicine. Prolozone therapy uses injections of ozone gas and vitamin B12 to stimulate a healing response in injured tissue. Prolozone therapy requires fewer injections than prolotherapy.