Peripheral neuropathy, or nerve damage, can respond to pain relief treatment, but in some cases, the condition goes away on its own, according to Drugs.com. Peripheral neuropathy can impact legs, feet, hands and arms as well as internal organs such as the lungs and bladder. Injuries, trauma, infections, alcohol abuse and other chronic conditions, including cancer and rheumatoid arthritis, cause the condition. Certain medications and treatments, including chemotherapy, heart medicines and HIV treatments, may put patients at a higher risk.
Sciatic nerve pain that radiates down the leg often improves on its own without treatment, according to WebMD. Sciatica occurs either when a herniated disk puts pressure on the sciatic nerve root or as a symptom of spinal stenosis, arthritis or nerve damage. Pain that extends from the lower back and buttocks down the leg and through the foot is indicative of sciatica. Individuals may feel weakness, numbness or tingling in addition to pain.
Doctors treat sciatic pain with medications such as steroids, muscle relaxers and opiates, according to WebMD. Standing or sitting in one position for extended periods of time may worsen symptoms. It often helps to lay down or extend the spine with exercise such as walking. Physical therapy is effective for some patients, but surgery may be necessary in severe cases.