There may be an interaction between ibuprofen and blood pressure medications; patients who require both should check with their doctors for an alternative to ibuprofen, states WebMD. Ibuprofen is classified as a nonsteroidal anti-inflammatory drug and is used to manage pain and swelling. Although ibuprofen is the generic name of the medication, this OTC drug is also available under brand names including Motrin and Advil, notes MedicineNet.
Ibuprofen can interact with hypertension medication because it causes fluid retention in the body, leading to kidney issues and a marked elevation in blood pressure. Patients who use hypertension medication and a nonsteroidal anti- inflammatory drug may have to take another drug as directed by their doctors to avoid this problem. Acetaminophen may be a possible substitution for ibuprofen, according to WebMD.