According to Drugs.com, Diflucan should not be taken at the same time as another antifungal medication. WebMD states that Monistat or tioconazole is an azole antifungal medication.
EMedicineHealth notes that Diflucan, or fluconazole, is an antifungal medication used to treat fungus, which can invade any part of the body. The site explains that Diflucan can also be used to prevent fungal infections in individuals with weak immune systems.
Although symptoms can clear up within a few days, eMedicineHealth reminds patients to complete the entire prescription, otherwise the infection may not be completely cleared. EMedicineHealth states that skipping a dose can increase the risk of further infection that is resistant to antifungal medications.