Clonidine, when taken as prescribed, cannot be used to achieve a high nor is it addictive, according to Project Know. Increasingly, however, there are contradictory reports of this medication being consumed in high dosages or in combination with other drugs to simulate a high or extend the effects of a high. These reports come primarily from a select group of former or current opiate users.
Clonidine is a blood pressure medication that lowers blood pressure by decreasing the heart rate and relaxing constricted blood vessels. Clonidine comes in pill or patch form. To prevent misuse, doctor's often prescribe a patch. Although not approved by the FDA as a drug and alcohol dependency treatment medication, it is prescribed by doctors to facilitate withdrawal treatment, notes Project Know. Clonidine, in high dosages, can cause lethal changes in blood pressure and, while it is not addictive, can cause a physical dependency. It is not advised to discontinue usage abruptly or without a doctor's consent.
If any of the following side effects appear, a doctor must be sought immediately: rash or hives, swelling, difficulty breathing, difficulty swallowing or hoarseness, slurred speech, fainting, confusion, drowsiness or weakness, according to MedlinePlus. Clonidine has also been prescribed to help control Tourette's syndrome and attention deficit hyperactivity disorder.