Clindamycin would not be a first choice for an uncomplicated bladder or urinary tract infection. If a bladder infection remained untreated, leading to sepsis, clindamycin might be indicated if the bacteria in question were susceptible to it, according to WebMD.
Clindamycin is an antibiotic used to treat serious bacterial infections, according to RxList.com. Nausea, vomiting and diarrhea are common side effects. The drug carries a black-box warning relating to the risk of developing severe diarrhea, colitis, toxic megacolon and other life-threatening intestinal disorders during treatment. Anyone developing severe, watery diarrhea with or without blood in the stool should discontinue the drug and contact a physician as soon as possible.