Traumatic injuries, such as a fracture or dislocation of the thigh or hip bone, may cause pain in the front of the thigh, according to Healthgrades. Bone infections and septic arthritis are infections that can cause thigh pain, while neuropathy can cause pain through nerve dysfunction or damage.
Certain injuries, such as dislocation of the hip joint, can cause significant pain in the thigh, according to Healthgrades. A pull or strain of the groin or the quadriceps muscle in the front of the leg may also be the root of pain in the front of the thigh. Although obvious, a laceration or scrape on the front of the leg can cause pain as well. An overuse injury, such as tendinitis, may also be a possible cause.
Bacterial infection of a laceration or sore can also lead to pain in the front of the thigh, notes Healthgrades. Skin infections may cause superficial pain on the skin of the front of the thigh. Infection of the hip or knee joint can lead to septic arthritis, which may lead to thigh pain. Other causes of pain in the front of the thigh include compartment syndrome of the quadriceps, tears in the cartilage of the knee and deep vein thrombosis.