Calorie restriction, coupled with excellent nutrition, may slow the aging of the human heart. In a study published in the "Journal of the American College of Cardiology," subjects on a calorie-restricted diet experienced lower blood pressure, less inflammation and better diastolic function than those on a typical Western diet.
Studies done on mice have shown that calorie-restricted diets may promote longevity by increasing the production of nitric oxide and other important chemicals. However, these findings are not necessarily relevant to humans.
Current research suggests that calorie restriction only slows the aging process when coupled with proper nutrition. Calorie restriction coupled with poor nutrition can, in fact, speed the aging process.