Bone cancer does not cause skin lesions, according to MedicineNet, Mayo Clinic, the American Cancer Society and WebMD. The chief symptom of bone cancer is pain that worsens over time and wakes the patient up at night. The patient eventually limps if the cancer is in a leg bone.
Other symptoms of bone cancer are swelling that develops in the affected area that doesn't appear till well after the pain begins, says the American Cancer Society. The bone may eventually fracture, though this is uncommon. There is weakness, numbness or tingling if the tumor presses on a spinal nerve and tiredness and weight loss if the tumor metastasizes.