Sodium lauryl sulfate does not trigger an allergic reaction from the body's immune system; however, the chemical can cause dryness and exacerbate skin eczema, according to HowStuffWorks. Sodium lauryl sulfate can break down natural skin oils, which in turn can lead to irritation.
Certain animal studies have shown that sodium lauryl sulfate can cause eye irritation, according to Drugs.com. Oral health products, such as toothpastes and mouth rinses, that contain sodium lauryl sulfate may also cause canker sores in certain individuals. In addition to personal hygiene products, the chemical is a common ingredient in floor cleaning products and industrial strength de-greasing solutions.