Holes in the heart are also known as septal defects, and in the absence of other complications, they are regarded as simple congenital heart defects, according to the National Institutes of Health. Examples of septal defects include atrial septal defect and ventricular septal defect.
An atrial septal defect is a hole in the part of the septum that separates the upper chambers of the heart, while a ventricular septal defect is a hole in the part of the septum that separates the lower chambers of the heart, states the National Institutes of Health. Both types of defects can vary in size. Small defects do not require any special treatment and may close on their own, while large defects may call for open-heart surgery.