The heart'saortic valve becomescalcified when deposits of calcium form on it. These calcium deposits typically affect the leaflets of the valve, thus preventing the proper closing and opening of the aortic valve, according to Healthline. This may lead to a condition known as valvular regurgitation or insufficiency where blood leaks back into the left ventricle while entering the aorta.
Most people above the age of 65are the most affected, notes Mayo Clinic. Calcification reduces aortic elastance, thus impairing cardiovascular hemodynamics and leading to significant mortality and morbidity in the form of congestive heart failure, cardiac hypertrophy, hypertension, myocardial ischemia,aortic stenosis and heart disease.