Q:

What is a BUN-to-Creatinine Ratio blood test?

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Quick Answer

A BUN/Creatinine Ratio blood test is used in the differential diagnosis of acute or chronic renal disease, the diagnosis of reduced renal profusion, gastrointestinal bleeding, trauma, liver disease and urinary tract obstructions, according to Quest Diagnostics. The test looks for changes in the ratio of blood urea nitrogen to creatinine.

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Full Answer

An increased BUN/Creatinine Ratio indicates reduced renal profusion, urinary tract obstruction and gastrointestinal bleeding. A decrease in the BUN/Creatinine Ratio indicates liver disease.

Chronic kidney disease gradually worsens over many months and years. Loss of function in the kidneys is a slow process, and renal disease often has few or no symptoms at the start of the disease, according to MedlinePlus. Symptoms typically become apparent during the end stage of renal disease. During end stage renal disease, the kidneys are no longer able to remove waste from the body. Dialysis or a kidney transplant are medically necessary at this point.

According to MedlinePlus, symptoms of kidney disease that occur after the kidneys have started to fail include abnormally dark or light skin, bone pain, drowsiness, numbness, foul breath and excessive thirst. Diabetes and high blood pressure are the most common causes of kidney disease. Autoimmune disorders, birth defects, toxic chemicals, certain medicines, problems with the arteries flowing to the kidneys and backward flow of urine into the kidneys (reflux nephropathy) are all causes of renal disease.

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Related Questions

  • Q:

    How do you understand high BUN-to-creatinine test results?

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    A high blood urea nitrogen-to-creatinine ratio may indicate dehydration, congestive heart failure, gastrointestinal bleeding or increased dietary protein, according to the American Association for Clinical Chemistry. Normal BUN-to-creatinine ratios range from 10 to 1 up to 20 to 1. A higher-than-normal reading generally means a patient has decreased blood flow to the kidneys.

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  • Q:

    Where do you get a blood test done?

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    Blood tests are done at a doctor's offices and clinics or at a local lab, such as LabCorp or Quest Diagnostics, notes Fox News. As of 2015, LabCorp and Quest Diagnostics have locations in every U.S. state and the District of Columbia, state their respective websites.

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  • Q:

    What can cause an increased INR?

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    Causes of an increased international normalized ratio, or INR, include blood-thinning medications and medical conditions such as liver disease, vitamin K deficiency and disseminated intravascular coagulation, according to Lab Tests Online. A high INR means that blood is too thin, the most common cause of which is blood-thinning medications, notes HealthTap.

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  • Q:

    What is the BUN-to-creatinine ratio used to measure?

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    Doctors use blood urea nitrogen to creatinine ratio to determine the working condition of the kidneys, as WebMD explains. A BUN test helps to determine the amount of nitrogen excreted from the blood through urea, while a blood creatinine test measures the level of creatinine. Doctors also use the BUN-to-creatinine ratio test to check for possible problems such as dehydration that may alter normal levels of BUN and creatinine.

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