High creatine levels cannot be brought down until further tests have been conducted to determine the cause of the elevated levels, according to Mayo Clinic. Decreased kidney function is the most common cause for higher creatine levels, but they may also be due to dehydration and low blood volume.
Creatine is produced naturally by the body and is stored in the muscles, but athletes may ingest higher amounts to enhance athletic performance and to encourage the building of muscle, states WebMD. The chemical is found naturally in such foods as fish and meat, but it may also be ingested through supplements and sports drinks.
Creatine is sometimes used in the treatment of Parkinson's disease as well as various issues with metabolizing creatine due to certain disorders, according to WebMD. Some clinical studies claim that creatine may be beneficial for congestive heart failure, diabetes, depression and various muscle disorders.
Creatine collects water from various parts of the body and draws it toward the body's muscles, WebMD explains. This is why high levels of creatine, resulting from ingestion of high doses of the supplement, can lead to kidney problems and dehydration, in addition to heart and liver issues. Because of this, individuals taking creatine supplements are advised to drink plenty of fluids.