As of 2015, brands of antifungal nail polish available in the United States include Fiore RX and Penlac. Generic formulas of ciclopirox or amorolfine antifungal agents may also be used to treat nail fungus, according to the United States National Library of Medicine.
Fiore RX nail polish contains the active ingredient undecylenic acid, an antifungal agent derived from castor oil, notes the Fiore RX website. Undecylenic acid is less effective than similar antifungals on the market, notes Mayo Clinic.
Penlac nail lacquer is a prescription nail lacquer with the active ingredient ciclopirox in an 8 percent concentration, according to the United States National Library of Medicine. Cicplopirox may also be available under the brand name Loprox. This antifungal agent is suitable for treatment of mild to moderate fungal infections of the nail bed. Penlac nail lacquer should be applied to the nails daily for up to 48 weeks for full treatment of fungal infections of the nail bed. This nail polish is flammable and should be kept away from heat sources or open flames.
A generic nail lacquer containing a 5 percent concentration of amorlofine may also be prescribed. Branded amorlofine nail lacquers are available only in Europe as of 2015, notes Drugs.com. While ciclopirox works by disrupting enzyme production in fungal cells, amorolfine works by disrupting the cell wall, thereby causing the death of the fungus, notes the United States National Library of Medicine.